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Suresh, H. M.
- Effect of Cassia auriculata Linn Flowers Against Alloxan-induced Diabetes in Rats
Abstract Views :567 |
PDF Views:814
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Journal of Natural Remedies, Vol 5, No 2 (2005), Pagination: 132-136Abstract
Objective : To evaluate the antidiabetic activity of flowers of Cassia auriculata Linn against alloxaninduced diabetes in rats and to isolate the bioactive constituents from the activity guided fraction. Materials and methods : The ethanol & aqueous extracts of flowers of Cassia auriculata were obtained by continuous soxhlet extraction & cold maceration respectively. Each extract was assessed for antidiabetic activity by estimating serum glucose level in diabetic rats. The active ethanol extract was subjected to qualitative chemical analysis to identify the active phytoconstituents. The sterol; β sitosterol, was isolated from ethanol extract by column chromatography. Results : In alloxan-induced diabetic rats the ethanol extract (250 mg / kg, p.o.) showed significant (P<0.001) antidiabetic activity as observed from serum glucose level in diabetic rats. However, the aqueous extract (250 mg / kg, p.o.) did not significantly reduce the serum glucose level in diabetic rats. The ethanol extract showed the presence of sterols, triterpenoids, flavonoids and tannins. Conclusion : From the results, it is revealed that, the active ethanol extract of Cassia auriculata flowers is worthwhile to develop the bioactive principle for diabetes mellitus and it is also concluded that the isolated sterol; β sitosterol, could be attributed for antidiabetic activity.Keywords
Cassia auriculata, Flowers, Antidiabetic, Sterols, Ethanol Extract- Laxative Activity of Cassia auriculata Pods in Rats
Abstract Views :513 |
PDF Views:402
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Journal of Natural Remedies, Vol 7, No 1 (2007), Pagination: 150-154Abstract
Objective: To evaluate ethanol extract of pods of Cassia auriculata Linn at different doses (100, 200 mg / kg, p.o.) for laxative activity in rats. Materials and Methods: The ethanol extract of pods of Cassia auriculata was obtained by continuous soxhlet extraction and further assessed for laxative activity by charcoal meal test and feacal output in experimental rats and compared with standard senna. The extract was subjected to qualitative chemical analysis to identify the phytoconstituents. Results: Upon evaluation of Laxative activity on experimental animals, the ethanol extract at the dose 200 mg / kg, p.o. showed significant (P<0.001) laxative activity as observed from different evaluation parameters. However, the same at the dose 100 mg / kg, p.o. was less significant. The ethanol extract showed the presence of flavonoids, triterenoids, tannins, sterols and anthracene derivatives. Conclusion: From the results, it is revealed that, the active ethanol extract (200 mg / kg, p.o.) of Cassia auriculata pods is worthwhile to develop the bioactive principle for laxative activity and it is also concluded that, the anthracene derivatives present, could be attributed for the laxative activity.Keywords
Cassia auriculata, Pods, Laxative, Anthracene Derivatives, Ethanol Extract- Laxative Activity of Cassia auriculata Pods in Rats
Abstract Views :413 |
PDF Views:413
Authors
Source
Journal of Natural Remedies, Vol 7, No 1 (2007), Pagination: 150-154Abstract
Objective: To evaluate ethanol extract of pods of Cassia auriculata Linn at different doses (100, 200 mg / kg, p.o.) for laxative activity in rats. Materials and Methods: The ethanol extract of pods of Cassia auriculata was obtained by continuous soxhlet extraction and further assessed for laxative activity by charcoal meal test and feacal output in experimental rats and compared with standard senna. The extract was subjected to qualitative chemical analysis to identify the phytoconstituents. Results: Upon evaluation of Laxative activity on experimental animals, the ethanol extract at the dose 200 mg / kg, p.o. showed significant (P<0.001) laxative activity as observed from different evaluation parameters. However, the same at the dose 100 mg / kg, p.o. was less significant. The ethanol extract showed the presence of flavonoids, triterenoids, tannins, sterols and anthracene derivatives. Conclusion: From the results, it is revealed that, the active ethanol extract (200 mg / kg, p.o.) of Cassia auriculata pods is worthwhile to develop the bioactive principle for laxative activity and it is also concluded that, the anthracene derivatives present, could be attributed for the laxative activity.Keywords
Cassia auriculata, Pods, Laxative, Anthracene Derivatives, Ethanol Extract- Anticonvulsant Effect of Cyperus rotundus Linn Rhizomes in Rats
Abstract Views :509 |
PDF Views:612
Authors
S. I. Shivakumar
,
H. M. Suresh
,
C. S. Hallikeri
,
B. C. Hatapakki
,
J. S. Handiganur
,
Kuber Sankh
,
B. Shivakumar